Clinical Question:
Does a tea prepared from leaves of jambolan, Syzygium cumini (L.) Skeels,
has an antihyperglycaemic effect in patients with type 2 diabetes mellitus?
Bottom Line:
Tea prepared from leaves of S. cumini has no hypoglycaemic effect.
Reference:
The efficacy of folk medicines in the management of type 2 diabetes
mellitus: results of a randomized controlled trial of Syzygium cumini (L.)
Skeels.Teixeira CC, Fuchs FD, Weinert LS, Esteves J.J Clin Pharm Ther. 2006
Feb;31(1):1-5.
Study Design:
Randomized Controlled Trial
Synopsis:
To investigate whether a tea prepared from leaves of jambolan, Syzygium
cumini (L.) Skeels, has an antihyperglycaemic effect in patients with type 2
diabetes mellitus. Patients with type 2 diabetes mellitus were enrolled in a
double-blind, double-dummy, randomized clinical trial. The three
experimental groups received a tea prepared from leaves of S. cumini plus
placebo tablets, placebo tea plus glyburide tablets or placebo tea plus
placebo tablets. In total, 27 patients were allocated to one of the
treatment groups and followed for 28 days. Fasting blood glucose levels
decreased significantly with glyburide and did not change with S. cumini tea
or placebo. Body mass index, creatinine, gamma-glutamyl transferase,
alkaline phosphatase, aspartate aminotransferase (SGOT), alanine
aminotransferase (SGPT), 24-h glicosuria, 24-h proteinuria, triglycerides,
total, low-density lipoprotein and high-density lipoprotein cholesterol did
not vary significantly between the different groups. |