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Female Genitalia

SYMPTOMS:
  • PAST HISTORY:
    • Gravida: Number of pregnancies
    • Para: Number of live deliveries
    • Number of planned and spontaneous abortions.
  • ABNORMALITIES in MENSTRUATION: Normal menstrual period = about 40 mL of blood.
    • Amenorrhea: No menstruation for 3 months or more.
      • Primary Amenorrhea: Failure of menarche
        • Kallman's Syndrome: Primary GnRH deficiency
        • Turner's Syndrome: XO
        • Testicular Sensitization Syndrome: Androgen insensitivity. Genotypic male may be diagnosed with testicular feminization when he presents as a teenager with primary amenorrhea.
        • Imperforate hymen
        • Congenital malformations of GU tract: Uterine agenesis, vaginal malformations.
      • Secondary Amenorrhea: Amenorrhea occurring any time after menarche has occurred.
        • Environmental Factors:
          • Weight-reduction amenorrhea: Anorexia and related disorders, malnutrition.
          • Psychogenic amenorrhea
          • Exercise-induced amenorrhea
          • Post-pill amenorrhea
        • Pituitary Disease:
          • Prolactinoma
          • Sheehan Syndrome = post-partum hemorrhage causing pituitary infarct from lack of blood-flow and increased pituitary demand.
        • Premature ovarian failure: Menopause occurring before age 35. Can be caused oophoritis (mumps virus), or may be idiopathic.
        • Polycystic Ovary Syndrome
        • Asherman's Syndrome: Amenorrhea caused by intrauterine adhesions (synechiae) that obliterate part of the uterine cavity. This can occur subsequent to vigorous dilatation and curettage (D&C) of the endometrium.
    • Hypomenorrhea: Decrease in volume of flow or duration of periods.
    • Menorrhagia, Hypermenorrhea: Abnormally heavy volume of flow or abnormally long periods.
      • Most common causes: Uterine fibroids (leiomyomas), PID, Endometriosis, IUD
    • Metrorrhagia: Bleeding at mid-cycle. It is usually precipitated by the drop in estrogen that occurs after ovulation.
    • Dysmenorrhea: Painful menstruation. Symptoms = lower abdominal pain, nausea, vomiting, fatigue, diarrhea.
      • Primary Dysmenorrhea: Unexplained, idiopathic dysmenorrhea. Believed to be caused by high uterine levels of PGE2.
      • Secondary Dysmenorrhea: Endometriosis, PID, imperforate hymen, uterine polyps, adhesions.
    • Dysfunctional Uterine Bleeding (DUB): Abnormal uterine bleeding in which no etiologic agent can be found after history and pelvic exam.
  • OTHER THINGS RELATING TO MENSTRUATION:
    • MENOPAUSE:
    • PRE-MENSTRUAL SYNDROME:
  • NON-MENSTRUAL VAGINAL BLEEDING: Bleeding not related to menstruation. When vaginal bleeding presents, we must determine whether it is menstrual or non-menstrual.
    • Post-Menopausal Bleeding: Consider uterine cancer, cervical cancer. Atrophic vaginitis if patient is not on ERT.
    • Pregnancy, either intrauterine or ectopic, may cause bleeding for a variety of reasons.
    • Birth control methods: IUD, breakthrough bleeding with pill.
  • PELVIC PAIN:
    • ACUTE PELVIC PAIN:
      • Mittelschmerz: Pelvic pain occurring at mid-cycle and related to ovulation.
      • Torsion of Ovary: Cystic ovary can get large and twist on itself, cutting off its blood supply ------> acute-onset pelvic pain.
      • Ruptured tubal pregnancy.
    • CHRONIC PELVIC PAIN:
      • Endometriosis: Dysmenorrhea, dyspareunia, infertility. Often have chronic pelvic pain, associated with the location of the ectopic glandular tissue.
        • Pain of endometriosis tends to be constant, and tends to radiate to coccyx, lower back.
        • Onset of disease is usually between 25 and 40. Undifferentiated dysmenorrhea often presents younger than age 25.
  • URINARY TRACT INFECTIONS:
  • PREGNANCY and INFERTILITY:
    • Early Pregnancy: Common symptoms
      • Secondary amenorrhea. Patient may also see reduced flow, or slight vaginal bleeding at time of normal period.
      • Morning Sickness: Nausea and vomiting
      • Breast tenderness
      • Urinary frequency: cause may be anatomical or hormonal.
      • Constipation
      • Weight change: weight loss is common in early pregnancy, followed by weight gain later.
    • Late Pregnancy:
      • Chloasma: Characteristic darkening of skin around eyes, nose, cheeks. Darkening also occurs in areolae, skin between umbilicus and pubic ridge.
      • Striae Gravidarum: Stretch marks of pregnancy.
      • Spider angiomas may occur in skin, because of high estrogen.
    • Pelvic Changes with Pregnancy:
      • Chadwick's Sign: Blue or purple discoloration of the vagina.
      • Leukorrhea: Clear or white vaginal discharge with faint musty odor. It may occur during pregnancy or in other circumstances.
      • Goodell's Sign: Bluish discoloration and softening of the cervix.
      • Braxton Hicks Contractions: Painless uterine contractions occurring after the 28th week.
      • Quickening: The first fetal movement of which the patient is aware. Normally occurs at 18 weeks during first pregnancy, and at 16 weeks in subsequent pregnancies.
    • Hydatidiform Mole: Signs of a molar pregnancy:
      • Uterus increases rapidly in size shortly after implantation.
      • Persistent vaginal bleeding, no fetal movement, and no fetal heart tones by 12 weeks.
      • Nausea and vomiting more intense than usual.
      • Grape like clusters of tissues may be expelled through the vagina.
  • ABNORMALITIES in SEXUAL FUNCTION:
    • Vaginismus: Spasmodic, guarding contraction of vagina upon attempt of intercourse. Often occurs subsequent to rape or trauma.
  • VAGINAL DISCHARGE and ITCHING
    • Physiologic Discharge: Clear or white discharge occurring at midcycle.
    • Trichomonas Vaginalis:
      • Discharge: Gray, foamy discharge having bad odor.
      • Mucosa: Red, strawberry cervix.
      • Confirm: Confirm with wet-mount (saline suspension microscopy).
    • Gonorrhea:
      • Discharge: Profuse mucoid discharge with foul odor.
      • Mucosa: Red, tender mucosa.
      • Confirm: Confirm with culture.
    • Gardnerella Vaginalis: Also called Non-specific vaginitis. Co-infection with anaerobes usually also occurs.
      • Discharge: Gray or white, fishy odor
      • Mucosa: Normal
      • Confirm: Clue cells = large epithelial cells with many coccobacilli adherent to them.
    • Chlamydia:
      • Discharge: Little, yellow, mucous and pus in cervical canal.
      • Mucosa: Cervical erosion.
      • Confirm: FA stain of smear shows elementary bodies.
    • Candida Albicans: Yeast infection.
      • Discharge: White, cottage-cheese like
      • Mucosa: White patches stuck to a red base.
      • Confirm: KOH preparation, look for pseudohypha.
    • Atrophic Vaginitis: Estrogen deficiency
      • Discharge: Little discharge, some blood
      • Mucosa: Atrophic, pale or red.
      • Confirm: history, age.
  • PELVIC RELAXATION: Loss of pelvis support due to atrophy of muscular viscera,
    • Urethrocele: Urethra herniates into the vaginal canal.
    • Cystocele: Bladder herniates into the vaginal canal.
    • Rectocele: Rectum herniates into the vaginal canal.
    • Uterine Prolapse: Descent of the uterus into the vaginal canal. Graded from 1 (mild) to 3 (uterus descends past the vulva).
  • HIRSUTISM

 

 

 
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